Endocrine Abstracts

Tissue kallikrein is a serine protease involved in the generation of kinins in kidneys, colon, salivary glands, pancreas and blood vessels which have vasodilator roles and influence ion transport. Abnormal renal synthesis and urinary excretion of tissue kallikrein have been linked to diabetes and hypertension. This study’s objective was to produce mAbs against native forms of prokallikrein and active kallikrein in order to study the expression of tissue kallikrein in diff...